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FrailSafe

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What we do

Ageing population is steeply increasing worldwide. A consequence of age related decline is the clinical condition of frailty. Frailty is a biological syndrome of decreased reserve and resistance to stressors, resulting from cumulative declines across multiple physiologic systems and causing vulnerability to adverse outcomes. Susceptibility to stressors is influenced by biological, behavioral, environmental, and social risk factors, with the main consequence being an increased risk for multiple adverse health outcomes, including disability, morbidity, falls, hospitalization, institutionalization, and death. However, frailty is a dynamic and not an irreversible process; it seems preventable, may be delayed, or reversed. Our understanding of frailty has markedly improved over the last five years, yet there are many issues yet to be resolved. FrailSafe aims to better understand frailty and its relation to co-morbidities; to identify quantitative and qualitative measures of frailty through advanced data mining approaches on multiparametric data and

use them to predict short and long-term outcome and risk of frailty; to develop real life sensing (physical, cognitive, psychological, social) and intervention (guidelines, real-time feedback, Augmented Reality serious games) platform offering physiological reserve and external challenges; to provide a digital patient model of frailty sensitive to several dynamic parameters, including physiological, behavioural and contextual; this model being the key for developing and testing pharmaceutical and non-pharmaceutical interventions; to create “prevent-frailty” evidence-based recommendations for the elderly; to strengthen the motor, cognitive, and other “anti-frailty” activities through the delivery of personalised treatment programmes, monitoring alerts, guidance and education; and to achieve all with a safe, unobtrusive and acceptable system for the ageing population while reducing the cost of health care systems.

Our social impact

Frailty is a syndrome that has an impact on everyone, those that will become frail but also their family members. The FrailSafe IT Platform enables older people to monitor their frailty levels and receive personalised recommendations, based on their health data, to prevent the onset of frailty.

By doing so, the FrailSafe IT Platform allows older persons to act in a pro-active and preventive approach but adopting healthy behaviours that will lead to a better livestyle.

Alongside such a postive approach, health professionals can access the FrailSafe IT Platform and their patients' health data to monitor their patients remotely.

Who's involved

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Nhu Tram
Project Officer

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This project was last updated 3 years ago
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DSI4EU, formally known as DSISCALE, is supported by the European Union and funded under the Horizon 2020 Programme, grant agreement no 780473.
All our work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , unless it says otherwise.
Nesta is a registered charity in England and Wales 1144091 and Scotland SC042833. Our main address is 58 Victoria Embankment, London, EC4Y 0DS
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